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Year Number of Results
2018 2
2019 1
2020 2
2021 3
2022 3
2023 6
2024 2

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16 results

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Page 1
Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming.
Christ A, Günther P, Lauterbach MAR, Duewell P, Biswas D, Pelka K, Scholz CJ, Oosting M, Haendler K, Baßler K, Klee K, Schulte-Schrepping J, Ulas T, Moorlag SJCFM, Kumar V, Park MH, Joosten LAB, Groh LA, Riksen NP, Espevik T, Schlitzer A, Li Y, Fitzgerald ML, Netea MG, Schultze JL, Latz E. Christ A, et al. Among authors: groh la. Cell. 2018 Jan 11;172(1-2):162-175.e14. doi: 10.1016/j.cell.2017.12.013. Cell. 2018. PMID: 29328911 Free PMC article.
Resolving sepsis-induced immunoparalysis via trained immunity by targeting interleukin-4 to myeloid cells.
Schrijver DP, Röring RJ, Deckers J, de Dreu A, Toner YC, Prevot G, Priem B, Munitz J, Nugraha EG, van Elsas Y, Azzun A, Anbergen T, Groh LA, Becker AMD, Pérez-Medina C, Oosterwijk RS, Novakovic B, Moorlag SJCFM, Jansen A, Pickkers P, Kox M, Beldman TJ, Kluza E, van Leent MMT, Teunissen AJP, van der Meel R, Fayad ZA, Joosten LAB, Fisher EA, Merkx M, Netea MG, Mulder WJM. Schrijver DP, et al. Among authors: groh la. Nat Biomed Eng. 2023 Sep;7(9):1097-1112. doi: 10.1038/s41551-023-01050-0. Epub 2023 Jun 8. Nat Biomed Eng. 2023. PMID: 37291433 Free PMC article.
The Itaconate Pathway Is a Central Regulatory Node Linking Innate Immune Tolerance and Trained Immunity.
Domínguez-Andrés J, Novakovic B, Li Y, Scicluna BP, Gresnigt MS, Arts RJW, Oosting M, Moorlag SJCFM, Groh LA, Zwaag J, Koch RM, Ter Horst R, Joosten LAB, Wijmenga C, Michelucci A, van der Poll T, Kox M, Pickkers P, Kumar V, Stunnenberg H, Netea MG. Domínguez-Andrés J, et al. Among authors: groh la. Cell Metab. 2019 Jan 8;29(1):211-220.e5. doi: 10.1016/j.cmet.2018.09.003. Epub 2018 Oct 4. Cell Metab. 2019. PMID: 30293776 Free article.
A chromatin-regulated biphasic circuit coordinates IL-1β-mediated inflammation.
Fok ET, Moorlag SJCFM, Negishi Y, Groh LA, Dos Santos JC, Gräwe C, Monge VV, Craenmehr DDD, van Roosmalen M, da Cunha Jolvino DP, Migliorini LB, Neto AS, Severino P, Vermeulen M, Joosten LAB, Netea MG, Fanucchi S, Mhlanga MM. Fok ET, et al. Among authors: groh la. Nat Genet. 2024 Jan;56(1):85-99. doi: 10.1038/s41588-023-01598-2. Epub 2023 Dec 13. Nat Genet. 2024. PMID: 38092881
In vitro induction of trained immunity in adherent human monocytes.
Domínguez-Andrés J, Arts RJW, Bekkering S, Bahrar H, Blok BA, de Bree LCJ, Bruno M, Bulut Ö, Debisarun PA, Dijkstra H, Cristina Dos Santos J, Ferreira AV, Flores-Gomez D, Groh LA, Grondman I, Helder L, Jacobs C, Jacobs L, Jansen T, Kilic G, Klück V, Koeken VACM, Lemmers H, Moorlag SJCFM, Mourits VP, van Puffelen JH, Rabold K, Röring RJ, Rosati D, Tercan H, van Tuijl J, Quintin J, van Crevel R, Riksen NP, Joosten LAB, Netea MG. Domínguez-Andrés J, et al. Among authors: groh la. STAR Protoc. 2021 Feb 24;2(1):100365. doi: 10.1016/j.xpro.2021.100365. eCollection 2021 Mar 19. STAR Protoc. 2021. PMID: 33718890 Free PMC article.
Dimethyl itaconate induces long-term innate immune responses and confers protection against infection.
Ferreira AV, Kostidis S, Groh LA, Koeken VACM, Bruno M, Baydemir I, Kilic G, Bulut Ö, Andriopoulou T, Spanou V, Synodinou KD, Gkavogianni T, Moorlag SJCFM, Charlotte de Bree L, Mourits VP, Matzaraki V, Koopman WJH, van de Veerdonk FL, Renieris G, Giera M, Giamarellos-Bourboulis EJ, Novakovic B, Domínguez-Andrés J. Ferreira AV, et al. Among authors: groh la. Cell Rep. 2023 Jun 27;42(6):112658. doi: 10.1016/j.celrep.2023.112658. Epub 2023 Jun 16. Cell Rep. 2023. PMID: 37330914 Free article.
Biomarkers of sustained systemic inflammation and microvascular dysfunction associated with post-COVID-19 condition symptoms at 24 months after SARS-CoV-2-infection.
Jacobs LMC, Wintjens MSJN, Nagy M, Willems L, Ten Cate H, Spronk HMH, van Kuijk SMJ, Ghossein-Doha C, Netea MG, Groh LA, van Petersen AS, Warlé MC. Jacobs LMC, et al. Among authors: groh la. Front Immunol. 2023 Oct 5;14:1182182. doi: 10.3389/fimmu.2023.1182182. eCollection 2023. Front Immunol. 2023. PMID: 37868959 Free PMC article.
oxLDL-Induced Trained Immunity Is Dependent on Mitochondrial Metabolic Reprogramming.
Groh LA, Ferreira AV, Helder L, van der Heijden CDCC, Novakovic B, van de Westerlo E, Matzaraki V, Moorlag SJCFM, de Bree LC, Koeken VACM, Mourits VP, Keating ST, van Puffelen JH, Hoischen A, Joosten LAB, Netea MG, Koopman WJH, Riksen NP. Groh LA, et al. Immunometabolism. 2021 Jun 30;3(3):e210025. doi: 10.20900/immunometab20210025. eCollection 2021. Immunometabolism. 2021. PMID: 34267957 Free PMC article.
d-2-Hydroxyglutarate is an anti-inflammatory immunometabolite that accumulates in macrophages after TLR4 activation.
de Goede KE, Harber KJ, Gorki FS, Verberk SGS, Groh LA, Keuning ED, Struys EA, van Weeghel M, Haschemi A, de Winther MPJ, van Dierendonck XAMH, Van den Bossche J. de Goede KE, et al. Among authors: groh la. Biochim Biophys Acta Mol Basis Dis. 2022 Sep 1;1868(9):166427. doi: 10.1016/j.bbadis.2022.166427. Epub 2022 May 6. Biochim Biophys Acta Mol Basis Dis. 2022. PMID: 35526742 Free article.
16 results